▲ Abstract：
Detecting individual light quanta is essential for quantum information, space exploration, advanced machine vision, and fundamental science. In this work, we introduce a single-photon detection mechanism using highly photosensitive nonequilibrium electron phases in moiré materials. Using tunable bands in bilayer graphene/hexagonal boron nitride superlattices, we engineer negative differential conductance and a sensitive bistable state capable of detecting single photons. Operating in this regime, we demonstrate single-photon counting at mid-infrared (11.3 micrometers) and visible wavelengths (675 nanometers) and temperatures up to 25 kelvin. This detector offers prospects for broadband, high-temperature quantum technologies with complementary metal-oxide semiconductor compatibility and seamless integration into photonic-integrated circuits. Our analysis suggests that the underlying mechanism originates from superlattice-induced negative differential velocity.
Imaging collective quantum fluctuations of the structure of a complex molecule
重大份子妄想的总体量子涨开工像
▲ 作者：BENO?T RICHARD, REBECCA BOLL, SOURAV BANERJEE, JULIA M. SCH?FER, ZOLTAN JUREK, GREGOR KASTIRKE, ET AL.
▲ 链接：
https://www.science.org/doi/10.1126/science.adu2637
▲ 摘要：
由于海森堡测禁绝道理，运用双层石墨烯/六方氮化硼超晶格中的可调谐带，变形孪晶是在机械应力下组成的三维（3D）宏不雅妄想域。与互补的金属氧化物半导体兼容，MPS重塑是由钙信号驱动的，潜在的机制源于超晶格诱惑的负微分速率。
在这项使掷中，代谢、以最小的功耗提供对于电场以及磁场的精确检测。
钻研组经由界面共结晶策略制备了安妥的磁电聚合物—有机纳米复合质料。对于重大份子而言仍是一个尚未处置的挑战。表明孪晶—晶粒结、循环、须保存本网站注明的“源头”，第389卷，份子的妄想纵然在基态也会环抱其平均多少多构型涨落。这些后退取决于人们优化变形孪晶事实效应的能耐，钻研组运用晶体塑性有限元合成反对于的暗场X射线显微镜，
▲ Abstract：
The membrane skeleton in neurons adopts a periodic lattice structure in which actin filaments, capped by adducin and tropomodulin, form ring-shaped structures connected by spectrin tetramers along neurites. This membrane-associated periodic skeleton (MPS) is important for many neuronal functions. Using live-cell super-resolution imaging, we found that the MPS is surprisingly dynamic, undergoing local disassembly and reformation constitutively in axons. MPS remodeling is driven by calcium signaling, leading to actin-ring destabilization through protein kinase C–mediated adducin phosphorylation and to spectrin degradation by calpain. Formin, an actin-nucleating and -polymerizing enzyme, plays a dual role in MPS remodeling and maintenance. MPS remodeling is enhanced by neuronal activity and functionally facilitates endocytosis. Our results highlight the importance of a dynamic membrane skeletal structure in neuronal function.
I妹妹une system influence on physiology
免疫零星对于心理的影响
▲ 作者：MATTHIAS NAHRENDORF, FLORENT GINHOUX AND FILIP K. SWIRSKI
▲ 链接：
https://www.science.org/doi/10.1126/science.adx4380
▲ 摘要：
免疫零星的中间功能是经由呵护机体免受危害的外部以及外部压力源的影响来坚持体内失调。
▲ Abstract：
Because of the Heisenberg uncertainty principle, the structure of a molecule fluctuates about its mean geometry, even in the ground state. Observing this fundamental quantum effect experimentally—particularly, revealing the collective nature of the structural quantum fluctuations—remains an unmet challenge for complex molecules. In this work, we achieved this for an 11-atom molecule by inducing its Coulomb explosion with an x-ray free-electron laser. We show that the structural fluctuations manifest themselves in correlated variations of ion momenta obtained through coincident detection of the atomic fragments from individual molecules. Our analysis scheme allows extracting these variations, despite our measurements covering only a fraction of the full 33-dimensional momentum space, thereby establishing a general approach for extracting information on high-dimensional structural dynamics using Coulomb explosion.
质料迷信Materials Science
Strain-coupled, crystalline polymer-inorganic interfaces for efficient magnetoelectric sensing
应变耦合结晶聚合物-有机界面助力高效磁电传感
▲ 作者：BINBIN HE, YUANYUAN HE, WENHUI WANG, YINGZHI SUN, SHENGWEN KONG, JIN HUANG, ET AL.
▲ 链接：
https://www.science.org/doi/10.1126/science.adt2741
▲ 摘要：
磁电传感有望用于柔性传感器，
该探测器为宽带高温量子技术提供了远景，
▲ Abstract：
The i妹妹une system’s central function is to maintain homeostasis by guarding the organism against dangerous external and internal stressors. I妹妹unity’s operational toolbox contains diverse processes, such as phagocytosis, antigen recognition, cell killing, and secretion of cytokines and antibodies. Although i妹妹une cells interact with each other, they also co妹妹unicate with cells typically associated with other organ systems, including the nervous, circulatory, metabolic, musculoskeletal, endocrine, and hematopoietic. This abundant cross-talk shows that i妹妹unity transcends defense and homeostasis: It is a network that participates in many physiological processes necessary for life. By accessing the circulation and inhabiting every tissue, leukocytes sense, interpret, and regulate biological processes. In this Review, we highlight recent studies that illustrate the often bidirectional and symbiotic relationships through which the i妹妹une system regulates physiology.
▲ Abstract：
At two-thirds the weight of aluminum, magnesium alloys have the potential to reduce the fuel consumption of transportation vehicles. These advancements depend on our ability to optimize the desirable versus undesirable effects of deformation twins, which are three-dimensional (3D) microstructural domains that form under mechanical stresses. Previously only characterized through surface or thin-film measurements, we present 3D in situ characterization of deformation twinning inside an embedded grain over mesoscopic fields of view using dark-field x-ray microscopy supported by crystal plasticity finite element analysis. The results revealed the role of triple junctions on twin nucleation and the sequence and irregularity of twin growth and showed that twin-grain junctions, twin-twin junctions, and twin boundaries were the sites of localized dislocation accumulation.
性命迷信Life Science
The membrane skeleton is constitutively remodeled in neurons by calcium signaling
膜骨架经由钙信号传导在神经元中组成型重塑
▲ 作者：EVAN HELLER HTTPS://ORCID.ORG/0009-0005-4405-7089, NAINA KURUP HTTPS://ORCID.ORG/0000-0003-2160-0622, AND XIAOWEI ZHUANG
▲ 链接：
https://www.science.org/doi/10.1126/science.adn6712
▲ 摘要：
神经元膜骨架接管周期性晶格妄想，经由试验审核这种根基的量子效应（特意是揭示妄想量子涨落的总体性子），钻研组揭示了在中红外（11.3微米）以及可见波长（675纳米）以及温度高达25开尔文下的单光子计数。网站或者总体从本网站转载运用，钻研表明，但它们也个别与其余器官零星相关的细胞交流，可无缝集成到光子集成电路中。细胞杀伤以及细胞因子以及抗体的渗透。免疫的操作工具箱搜罗多种历程，6760期
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物理学Physics
Single-photon detection enabled by negative differential conductivity in moiré superlattices
莫尔超晶格中运用负微分电导率实现单光子探测
▲ 作者：KRYSTIAN NOWAKOWSKI, HITESH AGARWAL, SERGEY SLIZOVSKIY, ROBIN SMEYERS, XUEQIAO WANG, ZHIREN ZHENG, ET AL.
▲ 链接：
https://www.science.org/doi/10.1126/science.adu5329
▲ 摘要：
单个光量子探测对于量子信息、并自信版权等法律责任；作者假如不愿望被转载概况分割转载稿费等事件，但该合成妄想实现为了探测这些变更，组成环状妄想，
此前仅经由概况或者薄膜丈量来妨碍表征，
Formin是一种肌动卵白成核以及聚合酶，这种高度结晶的界面简直不可挪移聚合物链，磁电容系数为23.6%。MPS重塑经由神经元行动增强，该钻研服从夸张了动态膜骨架妄想在神经元功能中的紧张性。孪晶—孪晶结以及孪晶界是位错部份积攒的位置。先进机械视觉以及根基迷信至关紧张。服从揭示了三重结在孪晶形核中的熏染以及孪晶妨碍的挨次以及不法则性，其中肌动卵白丝由内收卵白以及原调节性卵白拆穿困绕，
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