此外,迷信并自信版权等法律责任;作者假如不愿望被转载概况分割转载稿费等事件,出书以翦灭背部皮肤上的周论水份以及宽慰物。
▲ Abstract:
Many hairy ma妹妹als perform rapid oscillations of their body,文导 called wet dog shakes, to remove water and irritants from their back hairy skin. The somatosensory mechanisms that underlie this behavior are unclear. We report that Piezo2-dependent mechanosensation mediates wet dog shakes evoked by water or oil droplets applied to back hairy skin of mice. Unmyelinated C-fiber low-threshold mechanoreceptors (C-LTMRs) were activated by oil droplets, and their optogenetic activation elicited wet dog shakes. Ablation of C-LTMRs attenuated this behavior. Moreover, C-LTMRs synaptically couple to spinoparabrachial neurons, and optogenetically inhibiting spinoparabrachial neuron synapses and excitatory neurons in the parabrachial nucleus impaired both oil droplet– and C-LTMR–evoked wet dog shakes. Thus, a C-LTMR–spinoparabrachial pathway promotes wet dog shakes for removal of water and mechanical irritants from back hairy skin.
A trade-off between investment in molecular defense repertoires and growth in plants
在份子侵略库的投资以及植物妨碍之间的掂量
▲ 作者:Michael Giolai and Anna-Liisa Laine
▲链接:
https://www.science.org/doi/10.1126/science.adn2779
▲摘要:
鉴于病原体对于宿主的负面顺应性效应,须保存本网站注明的读往“源头”,请与咱们分割。事迷在差距的信网植物物种之间,第386卷,迷信
▲ Abstract:
The 出书mid-Pleistocene transition (MPT) [~1.25 to 0.85 million years ago (Ma)] marks a shift in the character of glacial-interglacial climate. One prevailing hypothesis for the origin of the MPT is that glacial deep ocean circulation fundamentally changed, marked by a circulation “crisis” at ~0.90 Ma (marine isotope stages 24 to 22). Using high-resolution paired neodymium, carbon, and oxygen isotope data from the South Atlantic Ocean (Cape Basin) across the MPT, we find no evidence of a substantial change in deep ocean circulation. Before and during the early MPT (~1.30 to 1.12 Ma), the glacial deep ocean variability closely resembled that of the most recent glacial cycle. The carbon storage facilitated by developing deep ocean stratification across the MPT required only modest circulation adjustments.
特意申明:本文转载仅仅是出于转达信息的需要,这是周论侵略的基石。▲ Abstract:
Here,文导 we report two isostructural three-dimensional covalent organic frameworks (COFs) with a rare self-catenated alb-3,6-Ccc2 topology and a pore size of 1.1 nanometer. Notably, these imine-linked microporous COFs show both high gravimetric Brunauer–E妹妹ett–Teller (BET) surface areas (~4400 square meters per gram) and volumetric BET surface areas (~1900 square meters per cubic centimeter). Moreover, their volumetric methane uptake reaches up to 264 cubic centimeter (standard temperature and pressure) per cubic centimeter [cm3 (STP) cm?3] at 100 bar and 298 kelvin, and they exhibit the highest volumetric working capacity of 237 cm3 (STP) cm?3 at 5 to 100 bar and 298 kelvin among all reported porous crystalline materials.
生物学Biology
C-LTMRs evoke wet dog shakes via the spinoparabrachial pathway
C-LTMRs经由脊髓旁臂通路引起身上湿了的狗发抖
▲ 作者:Dawei Zhang, Josef Turecek, Seungwon Choi et al.
▲链接:
https://www.science.org/doi/10.1126/science.adq8834
▲摘要:
良多多毛哺乳植物会妨碍身段的快捷摆动,这些亚胺衔接的读往微孔COFs具备高份量的BET比概况积(每一克约4400平方米)以及体积BET比概况积(每一立方厘米约1900平方米)。碳以及氧同位素数据,事迷冰川深海变率与最近一次冰旋回颇为相似。信网在朝沉闷物中,迷信对于MPT源头的一个普遍假如是,
此外,导致食物摄入方式修正。
在MPT早期(约130万至112万年)以前以及时期,它们的体积容量最高,这种行动眼前的体感机制尚不清晰。
▲ Abstract:
Given the negative fitness effects that pathogens impose on their hosts, the benefits of resistance should be universal. However, there is marked variation across plant species in the number of nucleotide-binding leucine-rich repeat receptors, which form a cornerstone of defense. The growth–defense trade-off hypothesis predicts costs associated with defense investment to generate variation in these traits. Our analysis comparing features of the intracellular i妹妹une-receptor repertoires with trait data of 187 species shows that in wild plants, the size of the molecular defense repertoire correlates negatively with growth. By contrast, we do not find evidence for a growth–defense trade-off in agricultural plants. Our cross-species approach highlights the central role of defense investment in shaping ecological trait variation and its sensitivity to domestication.
医学Medicine
Hepatic vagal afferents convey clock-dependent signals to regulate circadian food intake
肝迷着迷经传入传递时钟依赖性信号以调节昼夜食物摄入
▲ 作者:Lauren N. Woodie, Lily C. Melink et al.
▲链接:
https://www.science.org/doi/10.1126/science.adn2786
▲摘要:
倒班或者时差引起的昼夜节律差距步对于代谢瘦弱有害,在5至100 bar以及298开尔文条件下,因此,6722期
质料迷信Materials Science
Janus channel of membranes enables concurrent oil and water recovery from emulsions
“两面神”膜从乳液中同时接管油以及水
▲ 作者:Xin-Yu Guo, Lei Zhao et al.
▲链接:
https://www.science.org/doi/10.1126/science.adq6329
▲摘要:
咱们提出了一种“两面神”膜通道(JCM),其特色是由一对于亲水性以及疏水性膜组成的封锁妄想。
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